In vitro Intestine Permeability Models in 4 Days

Watch the Webinar On-Demand

What if you could perform in vitro intestinal permeability assays in 4 days instead of 21?

What if paracellular permeability readouts would take you only 12 min instead of more than 5 hours?

When you create your intestinal tissue models in MIMETAS OrganoPlate® this is what you can expect.

Register for this webinar to learn how you can get the same results too.

In this webinar you will learn:

  • Limitations of current gut models
  • Comparison between 3D Caco-2 barrier tissue to standard 2D insert cultures
  • How to create 3D Caco-2 barrier tissue in the OrganoPlate
  • How to perform transport and barrier functions assays on the model

Selected Publications

  • Trietsch, S.J., Naumovska, E., Kurek, D. et al. Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes. Nat Commun 8, 262 (2017).
  • Beaurivage, C.; Naumovska, E.; Chang, Y.X.; Elstak, E.D.; Nicolas, A.; Wouters, H.; van Moolenbroek, G.; Lanz, H.L.; Trietsch, S.J.; Joore, J.; Vulto, P.; Janssen, R.A.; Erdmann, K.S.; Stallen, J.; Kurek, D. Development of a Gut-on-a-Chip Model for High Throughput Disease Modeling and Drug Discovery. Int. J. Mol. Sci. 2019, 20, 5661.