Modelling Angiogenesis From Start to Finish in the OrganoPlate®
Watch the Webinar On-Demand
What if you could study angiogenesis in vitro, modeling crucial in vivo aspects easily and quickly?
In this webinar you will learn about developing angiogeneis models in the OrganoPlate® platform, focusing on:
- How to develop perfusable angiogenic sprouts and assess their functionality
- How to mimic the tumor microenvironment in your models
- Overcoming the limitations of current angiogenesis models
Advantages of the OrganoPlate® platform include:
- Observe the onset and maturation of blood vessel formation
- Access to perfused lumina of angiogenic sprouts
- Apply stable gradients of factors
- Used by the entire top-10 pharma and 100s of academic research groups world wide
Selected Publications
- van Duinen V, Stam W, Borgdorff V, et al. Standardized and Scalable Assay to Study Perfused 3D Angiogenic Sprouting of iPSC-derived Endothelial Cells In Vitro. J Vis Exp. 2019;(153):10.3791/59678. Published 2019 Nov 6. doi:10.3791/59678
- van Duinen, V., Zhu, D., Ramakers, C. et al. Perfused 3D angiogenic sprouting in a high-throughput in vitro platform. Angiogenesis 22, 157–165 (2019). https://doi.org/10.1007/s10456-018-9647-0
- van Duinen, V., van den Heuvel, A., Trietsch, S.J. et al. 96 perfusable blood vessels to study vascular permeability in vitro . Sci Rep 7, 18071 (2017). https://doi.org/10.1038/s41598-017-14716-y